Medicines uses under review

The NCMAG Council makes decisions on the proposed use of cancer medicines.


These medicines uses are planned for review by NCMAG:

NCMAG125 – Paclitaxel

For use in combination with pertuzumab plus trastuzumab in adult patients with HER2-positive metastatic or locally recurrent unresectable breast cancer, who have not received previous anti-HER2 therapy or chemotherapy for their metastatic disease, and who are considered not fit enough for, or cannot tolerate docetaxel in this combination. (off-label use and off-patent medicine)

  • Council meeting date: to be confirmed
  • Planned publication date: to be confirmed

NCMAG 126 – Nivolumab plus ipilimumab

For use as neoadjuvant treatment of  mismatch repair deficient or microsatellite instability‑high locally advanced colon cancer which is judged to be borderline resectable. (off-label use)

  • Council meeting date: To be confirmed
  • Planned publication date: To be confirmed